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What exactly is the Endo cannabinoid system?

March 10, 2023

what exactly is the endocannabinoid system?

Discovered only 30 years ago, the endocannabinoid system (ECS) is known to be one of the largest networks of receptors in mammals. It's made up of CB1 and CB2 receptors, located in the brain, central nervous system, peripheral organs, and even our immune cells.

It's a part of everything that we do. The widespread distribution and number of these receptors affirm just how essential the ECS is to our overall health and well-being.

Cannabinoids are another piece of the ECS puzzle. Endocannabinoids are naturally produced in our bodies and bind to the CB1 and CB2 receptor sites. Our ECS is also influenced by phytocannabinoids, which come from plants-most commonly hemp. Raphael Mechoulam opened the floodgates for cannabis research with his discovery of THC in 1964.

CB1 and CB2 receptors hold the locks, and cannabinoids hold the keys to internal "homeostasis" -a balanced, all-encompassing wellness baseline. Essentially, ECS function is crucial to how we (and our pets) experience everyday life.

In fact, the International Review of Neurobiology suggests that a dysregulated ECS may be the culprit for several debilitating conditions.

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